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原著論文（リンクをクリックするとPubMedのAbstractが新しいウインドウで表示されます。）

 

 

2006

• Minaba, M., Ichiyama, S., Kojima, K., Ozaki, M. and Kato, Y.
  Activation of nematode G protein GOA-1 by the human muscarinic acetylcholine receptor M2 subtype. Functional coupling of G-protein-coupled receptor and G protein originated from evolutionarily distant animals.
  FEBS. J.  273, 5508-5516 (2006)
• Mangmool, S., Haga, T., Kobayashi, H., Kim, K.-M., Nakata, H., Nishida, M. and Kurose, H.
  Clathrin required for phosphorylation and internalization of β2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2).
  J. Biol. Chem.  281, 31940-31949 (2006)
• Nakamura, H., Kuroda, H., Saito, H., Suzuki, R., Yamori, T., Maruyama, K. and Haga, T.
  Synthesis and biological evaluation of boronic acid containing cis-stilbenes as apoptotic tubulin polymerization inhibitors.
  ChemMedChem  1, 729-740 (2006)
• Koike, D., Obinata, H., Yamamoto, A., Takeda, S., Komori, H., Nara, F., Izumi, T. and Haga, T.
  5-Oxo-eicosatetraenoic acid-induced chemotaxis: identification of a responsible receptor hGPCR48 and negative regulation by G protein G_12/13.
  J. Biochem.  139, 543-549 (2006)
• Takei, T., Okonogi, A., Tateno, K., Kimura, A., Kojima, S., Yazaki, K., and Miura, K.
  The effects of the side chains of hydrophobic aliphatic amino acid residues in an amphipathic polypeptide on the formation of α helix and its assocation.
  J. Biochem.  139, 271-278 (2006)
• Ichiyama, S., Oka, Y., Haga, K., Kojima, S., Tateishi, Y., Shirakawa, M., and Haga, T.
  The structure of the third intracellular loop of the muscarinic acetylcholine receptor M₂ subtype.
  FEBS Lett.  580, 23-26 (2006)

 

総説

2006  

• Takeda, S., Suga, H. and Haga, T.
  Screening of ligands for human GPCRs by the use of receptor-Gα fusion proteins, in “G protein-coupled receptors: structure, function, and ligand screening”, edited by Haga, T. and Takeda, S., CRC Press, Taylor & Francis Group, 37-66 (2006)

• Furukawa, H., Hamada, T., Hirota, H., Ishigur, M., and Haga, T.
  Determination of steric structure of muscarinic ligands bound to muscarinic acetylcholine receptors: approaches by TRNOE (transferred nuclear overhauser effect), in “G protein-coupled receptors: structure, function, and ligand screening”, edited by Haga, T. and Takeda, S., CRC Press, Taylor & Francis Group, 261-282 (2006)

　

学会発表

2006

• Kubo, Y., Yamada, H., Okuda, T., Haga, T.
  Topology model for the high-affinity choline transporter by site-directed chemical labeling
  第28回日本生物学的精神医学会、第36回日本神経精神薬理学会、第４９回日本神経化学会大会合同年会（2006年9月14日−16日、名古屋国際会議場）
• Kojima, S., Iwahara, A., and Yanai, H.
  Characterization of inhibitor-assisted folding of subtilisin BPN'
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (June 18 – 23, 2006, Kyoto International Conference Hall, Kyoto, Japan)
• Nakamura T., Sadakane Y., Haga, T., and Fujii, N.
  Kinetic study of racemization at Asp58 and Asp151 residues in recombinant human αA-crystallin
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (June 18 – 23, 2006, Kyoto International Conference Hall, Kyoto, Japan)
• Haga, T., Okuda, T., Kaitsuka, C., Osawa , C., Nishiyama, N., Yamada, H., Nakamura, T., Hayashi, K, Ito, S., Hamano, T., Sato, M., Ushio, T., Nishikawa, S., Kubo, Y., and Matsuda, H.
  Molecular characterization by mutagenesis of the high affinity choline transporter (CHT1)
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (June 18 – 23, 2006, Kyoto International Conference Hall, Kyoto, Japan)
• Hashimoto, Y., Morisawa, K., Saito, H., Jojima, E., Yoshida, N., and Haga, T
  A region in the third intracellular loop is involved in the recycling of internalized muscarinic acetylcholine receptor M₄ subtype
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (June 18 – 23, 2006, Kyoto International Conference Hall, Kyoto, Japan)
• Ichiyama, S., Nemoto, R., Tanabe, H., Okamura, M., Furukawa, H., and Haga, T.
  Effect of G proteinβγ subunits on the interaction of the muscarinic acetylcholine receptor M₂ or M₄ subtype with G protein Gα_{i 1} subunit
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (June 18 – 23, 2006, Kyoto International Conference Hall, Kyoto, Japan)
• Ichiyama, S., Nemoto, R., Haga, T.
  Interaction of muscarinic M2 receptor with G protein Gai 1 subunit in their fusion protein expressed in Escherichia coli: the effect of expression level
  12th International Conference on Retinal Proteins (June 4 – 8, 2006, Awaji Yumebutai International Conference Center, Hyogo, Japan)
• Hashimoto, Y., Morisawa, K., Saito, H., Jojima, E., Yoshida, N., and Haga, T..
  Dynamin-dependent internalization and recycling of M4 muscarinic acetylcholine receptors: the role of the third intracellular loop
  12th International Conference on Retinal Proteins (June 4 – 8, 2006, Awaji Yumebutai International Conference Center, Hyogo, Japan)
• 小島修一、切田祐子、若杉歩、村上匡史.
  ファージディスプレイ法によって得られたズブチリシン阻害ペプチドへの変異導入解析
  第6回日本蛋白質科学会年会（2006年4月24 – 26日、国立京都国際会館）
• Mangmool, S., 芳賀達也、西田基宏、黒瀬等
  クラスリンはGタンパク質共役受容体キナ−ゼ2(GRK)の活性化に必須である
  第79回日本薬理学会年会 (2006年3月8日-10日、パシフィコ横浜)

 

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