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原著論文（リンクをクリックするとPubMedのAbstractが新しいウインドウで表示されます。）

 

 

2006

  • Minaba, M., Ichiyama, S., Kojima, K., Ozaki, M. and Kato, Y.
    Activation of nematode G protein GOA-1 by the human muscarinic acetylcholine receptor M2 subtype. Functional coupling of G-protein-coupled receptor and G protein originated from evolutionarily distant animals.
    FEBS. J.  273, 5508-5516 (2006)
  • Mangmool, S., Haga, T., Kobayashi, H., Kim, K.-M., Nakata, H., Nishida, M. and Kurose, H.
    Clathrin required for phosphorylation and internalization of β2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2).
    J. Biol. Chem.  281, 31940-31949 (2006)
  • Nakamura, H., Kuroda, H., Saito, H., Suzuki, R., Yamori, T., Maruyama, K. and Haga, T.
    Synthesis and biological evaluation of boronic acid containing cis-stilbenes as apoptotic tubulin polymerization inhibitors.
    ChemMedChem 1, 729-740 (2006)
  • Koike, D., Obinata, H., Yamamoto, A., Takeda, S., Komori, H., Nara, F., Izumi, T. and Haga, T.
    5-Oxo-eicosatetraenoic acid-induced chemotaxis: identification of a responsible receptor hGPCR48 and negative regulation by G protein G12/13.
    J. Biochem.  139, 543-549 (2006)
  • Ichiyama, S., Oka, Y., Haga, K., Kojima, S., Tateishi, Y., Shirakawa, M., and Haga, T.
    The structure of the third intracellular loop of the muscarinic acetylcholine receptor M2 subtype.
    FEBS Lett.  580, 23-26 (2006)

 

総説

2006

  • Takeda, S., Suga, H., and Haga, T.
    Screening of ligands for human GPCRs by the use of receptor-Gα fusion proteins, in “G protein-coupled receptors: structure, function, and ligand screening”, edited by Haga, T. and Takeda, S., CRC Press, Taylor & Francis Group, 37-66 (2006)
  • Furukawa, H., Hamada, T., Hirota, H., Ishigur, M., and Haga, T.
    Determination of     steric structure of muscarinic ligands bound to muscarinic acetylcholine receptors: approaches by TRNOE (transferred nuclear overhauser effect), in “G protein-coupled receptors: structure, function, and ligand screening”, edited by Haga, T. and Takeda, S., CRC Press, Taylor & Francis Group, 261-282 (2006)

　

学会発表

2006

  • Kubo, Y., Yamada, H., Okuda, T., Haga, T.
    Topology model for the high-affinity choline transporter by site-directed chemical labeling
    第28回日本生物学的精神医学会、第36回日本神経精神薬理学会、第４９回日本神経化学会大会合同年会（2006年9月14日−16日、名古屋国際会議場）
  • Nakamura T., Sadakane Y., Haga, T.,Fujii, N.:
    Kinetic study of racemization at Asp58 and Asp151 residues in recombinant human αA-crystallin
    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (June 18 – 23, 2006, Kyoto International Conference Hall, Kyoto, Japan)
  • Haga, T., Okuda, T., Kaitsuka, C., Osawa , C., Nishiyama, N., Yamada, H., Nakamura, T., Hayashi, K, Ito, S., Hamano, T., Sato, M., Ushio, T., Nishikawa, S., Kubo, Y., Matsuda, H.
    Molecular characterization by mutagenesis of the high affinity choline transporter (CHT1)
    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (June 18 – 23, 2006, Kyoto International Conference Hall, Kyoto, Japan)
  • Hashimoto, Y., Morisawa, K., Saito, H., Jojima, E., Yoshida, N., and Haga, T
    A region in the third intracellular loop is involved in the recycling of internalized muscarinic acetylcholine receptor M4 subtype
    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (June 18 – 23, 2006, Kyoto International Conference Hall, Kyoto, Japan)
  • Ichiyama, S., Nemoto, R., Tanabe, H., Okamura, M., Furukawa, H., and Haga, T.
    Effect of G proteinβγ subunits on the interaction of the muscarinic acetylcholine receptor M2 or M4 subtype with G protein Gαi 1 subunit
    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress (June 18 – 23, 2006, Kyoto International Conference Hall, Kyoto, Japan)
  • Ichiyama, S., Nemoto, R., Haga, T.
    Interaction of muscarinic M2 receptor with G protein Gai 1 subunit in their fusion protein expressed in Escherichia coli: the effect of expression level
    12th International Conference on Retinal Proteins (June 4 – 8, 2006, Awaji Yumebutai International Conference Center, Hyogo, Japan)
  • Hashimoto, Y., Morisawa, K., Saito, H., Jojima, E., Yoshida, N., and Haga, T..
    Dynamin-dependent internalization and recycling of M4 muscarinic acetylcholine receptors: the role of the third intracellular loop
    12th International Conference on Retinal Proteins (June 4 – 8, 2006, Awaji Yumebutai International Conference Center, Hyogo, Japan)
  • Mangmool, S., 芳賀達也、西田基宏、黒瀬等
    クラスリンはGタンパク質共役受容体キナ−ゼ2(GRK)の活性化に必須である
    第79回日本薬理学会年会 (2006年3月8日-10日、パシフィコ横浜)

 

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