<学術論文> |
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Inaki, M., Utsugi, T., Onoda, F., Hanaoka, F., and Murakami, Y (2008) A novel class of temperature-sensitive mutants
generated by RNAi-mediated knockdowns. Biochem. Biophys. Res. Commun. 365: 472-477 |
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Yatagai, F., Umebayashi, Y., Homma, M., Sugasawa, K., Takayama, Y., and
Hanaoka, F. (2008) Mutagenic
radioadaptation in a human lymphoblastoid cell line.
Mutat. Res. 638: 48-55 |
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Hidaka, K., Yamada, M., Kamiya, H., Masutani, C., Harashima, H., Hanaoka,
F., and
Nohmi, T. (2008) Specificity of mutations induced by incorporation of oxidized dNTPs into
DNA by human DNA polymerase eta DNA Repair 7: 497-506 |
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Yasui, M.,
Suenaga, E., Koyama, N., Masutani, C., Hanaoka, F., Gruz, P., Shibutani, S., Nohmi, T., Hayashi, M., and Honma, M. (2008) Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA adduct,
during translesion synthesis catalyzed by human DNA polymerases. J. Mol. Biol. 377: 1015-1023 |
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Tsuji, Y., Watanabe, K., Araki, K., Shinohara, M., Yamagata, Y., Tsurimoto, T., Hanaoka, F., Yamamura, K., Yamaizumi, M., and Tateishi, S. (2008) Recognition of forked and single-stranded DNA structures by human RAD18
complexed with RAD6B
protein triggers its recruitment to stalled replication forks.
Genes Cells 13: 343-354 |
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Martomo, S.A., Saribasak, H., Yokoi, M., Hanaoka, F., and Gearhart, P.J.
(2008) Reevaluation
of the role of DNA polymerase theta in somatic hypermutation ofimmunoglobulin
genes.
DNA Repair 7: 1603-1608 |
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Ouchida, R., Ukai, A., Mori, H., Kawamura, K., Dolle, M.E., Tagawa, M., Sakamoto, A., Tokuhisa, T., Yokosuka, T., Saito, T., Yokoi, M., Hanaoka, F., Vijg, J., and Wang, J.Y. (2008)
Genetic analysis reveals an intrinsic property of the germinal center B
cells to generate A:T mutations. DNA Repair 7: 1392-1398 |
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Ohtsu, M., Kawate, M., Fukuoka, M., Gunji, W., Hanaoka, F., Utsugi, T., Onoda, F., and Murakami, Y. (2008) Novel DNA microarray system for analysis of nascent
mRNAs. DNA Res. 15: 241-251 |
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Fukumoto, Y., Dohmae, N., and Hanaoka, F. (2008) Schizosaccharomyces pombe Ddb1 recruits substrate-specific adaptor proteins through a novel protein motif, the DDB-box. Mol. Cell. Biol. 28: 6746-6756 |
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Masuda, K., Ouchida, R., Yokoi, M., Hanaoka, F., Azuma, T., and Wang, J.Y.
(2008) DNA polymerase
eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation. Eur. J. Immunol. 38: 2796-2805 |
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Nakamura, T., Sakai, M., Sadakane, Y., Haga, T., Goto, Y., Kinouchi, T., Saito, T., and Fujii,
N. (2008) Differential rate constants of racemization of aspartyl and asparaginyl
residues in human α-crystallin mutants. Biochim. Biophys. Acta 1784: 1192-1199 |
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Hashimoto, Y., Morisawa, K., Saito, H., Jojima, E., Yoshida, N., and Haga,
T. (2008) Muscarinic M4 receptor recycling requires a motif in
the third intracellular loop. J. Pharmacol. Exp. Therapeu. 325: 947 - 953 |
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Uehara, R., Hosoya, H., and Mabuchi, I. (2008) In vivo phosphorylation of regulatory light chain of myosin II in sea urchin eggs
and its role
in controlling myosin localization and function during cytokinesis. Cell Motil. Cytoskelet., 65: 100-115 |
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Shimi, T.,
Pfleghaar, K., Kojima, S., Pack, C., Solovei, I., Adam, S.A., Shumaker, D.K.,
Goldman,
A.E., Kinjo, M., Cremer, T., and Goldman, R.D. (2008) The A-type and B-type lamin networks: microdomains involved in chromatin organization and transcription. Genes Dev. 22: 3409-3421 |
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Matsuda, C., Kameyama, K., Suzuki, A., Mishima, W., Yamaji, S., Okamoto,
H., Nishino, I. and Hayashi, K.Y. (2008) Affixin activates
Rac1 via βPIX in C2C12 myoblast. FEBS Lett. 582: 1189-1196 |
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Aoki, G., Yamada, T.K., Arii, M., Kojima, S. and Mizoguchi, T. (2008) Requirement of Ala residues at g position in heptad sequence
of α-helix-forming peptide forformation of fibrous structure. J.
Biochem. 144: 15-19 |
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Usui, T., Ban, H. S., Kawada, J., Hirokawa, T., and Nakamura, H. (2008) Discovery of indenopyrazoles as EGFR and VEGFR-2
tyrosine kinase inhibitors by in silico high-throughput
screening. Bioorg.
Med. Chem. Lett. 18: 285-288 |
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Lee, C.-H., Jin, G. F., Yoon, J. H., Jung, Y. J., Lee, J.-D., Cho, S.,
Nakamura, H., and Kang, S.O. (2008) Synthesis and characterization of polar functional group substituted mono-
and bis-(o-carboranyl)-1,3,5-triazine derivatives. Tetrahedron Lett. 49: 159-164 |
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Uno, M., Ban, H. S., Nabeyama, W., and Nakamura, H. (2008) De novo design and synthesis of N-benzylanilines as new candidates for VEGFR tyrosine kinase
inhibitors. Org. Biomol. Chem. 6: 979-981 |
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Nakamura,
H., Ishikura, M., Sugiishi, T., Kamakura, T., and Biellmann, J.-F. (2008) Synthesis of mono- and 1,3-disubstituted allenes from propargylic amines
via
palladium-catalysed
hydride-transfer reaction. Org.
Biomol. Chem. 6: 1471-1477 |
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Nakamura, H., Saito, H., and Nanjo, M. (2008) Synthesis of 1,2-dihydroisoquinolines via palladium (0)-catalysed addition-cycloaddition
of
pronucleophiles to ortho-alkynylaldimines. Tetrahedron
Lett. 49: 2697-2700 |
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Nakamura, H., Lee, J.-D., Ueno, M., Miyajima, Y., and Ban, H.S. (2008) Synthesis of closo-dodecaboryl lipids and their liposomal formation for boron neutron capturetherapy. NanoBiotechnology
(invited) 3: 135-145 |
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Ban, H. S., Onagi, S., Uno, M., Nabeyama, W., and Nakamura, H. (2008) Allene as an alternative functional group for drug
design: effect of C-C multiple bonds conjugated with quinazolines on EGFR tyrosine kinase inhibition. ChemMedChem.
3: 1094-1103 |
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Sogabe, N., Oda, K., Nakamura, H., Orimo, H., Watanabe, H., Hosoi, T.,
and Goseki-Sone, M. (2008) Molecular effects of the tissue-nonspecific alkaline phosphatase gene polymorphism (787T>C) associated with bone mineral density. Biomed. Res. 29: 213-219 |
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Ryu, I., Matsubara, H., Nakamura, H., and Curran, D.P. (2008) Phase-vanishing methods based on fluorous phase screen. A simple way for efficient execution of organic synthesis. Chem.
Rec. 8: 351-363 |
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Nakamura, H., Sugiishi, T., and Tanaka, Y. (2008) Synthesis
of allenes via CuBr-catalyzed homologation of alk-1-ynes accelerated by
microwave. Tetrahedron
Lett. 49: 7230-7233 |
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Yajima, J., Mizutani, K., and Nishizaka, T. (2008) A torque component present in kinesin-5 revealed by 3D tracking. Nature
Struct. Mol. Biol. 15: 1119-1121 |
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Masaike, T., Koyama-Horibe, F., Oiwa, K., Yoshida, K., and Nishizaka, T.
(2008) Cooperative
three-step motions in catalytic subunits of F1-ATPase correlate with 80° and 40° substep
rotations. Nature Struct. Mol. Biol. 15: 1326-1333 |
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